Ex vivo infection of whole human lung with SARS-CoV-2

Interactive viewing of the single cell RNA-Seq data sets of five human lungs before (T0h) and after the ex vivo procedure (T10h):
Three lungs were infected with SARS-CoV-2 (donors 1, 2 & 3) and two lungs were processed as controls (donors 4 & 5). (more ...)

Gene Display Filters
Cluster Cell identities Sample
UMAP
Violin plot
C0
C1
C2
C3
C4
C5
C6
C7
C8
C9
C10
C11
C12
C13
C14
C15
C16
C17
C18
C19
C21
AMs-C0
AT2s-C1
AMs-C2
AMs-C3
MoMacs-C3
CD8+ T cells-C4
CD8+ T cells-C5
NK cells-C5
AMs-C6
AT2s-C6
cMos-C7
ncMos-C7
Blood ECs-C8
CD4+ T cells-C9
Cmos-C10
MoMacs-C11
cDC2s-C11
AT1s-C12
Stromal cells-C13
Transitional club/AT2s-C14
Club cells-C14
Blood ECs-C15
AMs-C15
B cells-C16
Ciliated cells-C17
Mast cells-C18
AMs-C19
AT2s-C21

Donor

Donor1
Donor2
Donor3
Donor4
Donor5

Time point

T0h
T10h

Donor / Time point

Donor1-T0h
Donor1-T10h
Donor2-T0h
Donor2-T10h
Donor3-T0h
Donor3-T10h
Donor4-T0h
Donor4-T10h
Donor5-T0h
Donor5-T10h
Colored by
Gene expression
Cluster
Cell identities

Donor
Time point
Donor / Time point